Nitric oxide metabolites in patients with asthma: induced sputum versus blood
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چکیده
منابع مشابه
Nitric oxide metabolites in patients with asthma: induced sputum versus blood.
Nitric oxide (NO) plays an important role in physiological regulation of the airways. The monitoring of airway inflammation has being observed in bronchial asthma directly, by sputum examination, and indirectly, by measurements in peripheral blood. To investigate the diagnostic value of these two methods, we compared NO metabolites in induced sputum and serum obtained in patients with asthma an...
متن کاملNitric oxide metabolites, eosinophils, and eosinophilic cationic protein in patients with asthma: sputum versus blood.
The monitoring of airway inflammation has assessed in bronchial asthma directly by sputum examination, and indirectly by measurements in peripheral blood. To investigate the diagnostic value of these two methods, we compared nitric oxide (NO) metabolites, eosinophils, and eosinophil cationic protein (ECP) in sputum and blood in patients with asthma and control subjects. Sputum and serum were ob...
متن کاملNitric oxide metabolites in induced sputum: a noninvasive marker of airway inflammation in asthma.
OBJECTIVE This study was designed to examine for nitric oxide (NO) metabolites in induced sputum as a marker of airway inflammation in asthmatic children. DESIGN. Prospective interventional SETTING Pediatric Allergy and Asthma Clinic of a tertiary care referral hospital in Northern India. SUBJECTS Twenty-one children with asthma who were not receiving corticosteroids for the preceding 3 mon...
متن کاملCorrelation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma.
BACKGROUND Eosinophils in induced sputum and exhaled nitric oxide (NO) are currently used as non-invasive markers in the assessment of airway inflammation in asthma. As both sputum eosinophils (%) and exhaled NO are raised in asthmatic subjects not receiving inhaled steroids and decreased following corticosteroid therapy, a relationship between them is plausible. METHODS Exhaled NO was measur...
متن کاملDiagnostic utility of inflammatory biomarkers in asthma: exhaled nitric oxide and induced sputum eosinophil count.
BACKGROUND Even though an inflammatory process is known to be the underlying cause of asthma, diagnosis is based on clinical history, reversible airway obstruction and bronchial hyperresponsiveness according to international guidelines. The fraction of exhaled nitric oxide (FE(NO)) and induced sputum eosinophil count (Eos%) have been used as non-invasive inflammatory biomarkers. OBJECTIVES Th...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 1999
ISSN: 0954-6111
DOI: 10.1016/s0954-6111(99)90059-8